The United States is a signatory in the Single Convention on Narcotic Drugs, 1961, and other international conventions intended to create effectual drug abuse prevention and control over international and domestic traffic in controlled substances.
Controlled substances produced and dispersed intra-state cannot be generally distinguished from controlled substances manufactured and distributed inter-state. As a consequence, it is not practicable to differentiate drug use and abuse, as far as control of the same goes, between controlled substances manufactured and distributed inter-state and those relating to intra-state.
The Controlled Substances Act (CSA) was ratified into law by the US Congress after it was put to table by the Drug Enforcement Administration or DEA as Title II of the Comprehensive Drug Abuse Prevention and Control Act of 1970 or simply the Comprehensive drug abuse prevention act.
The National Institute on Drug Abuse or NIDA was set up to lead the Nation to bring the control of science to manage drug abuse and addiction. It can be mentioned here that the illegal import, produce, distribution sharing, possession and inappropriate use of controlled substances have an adverse and injurious effect on the health and overall welfare of the people of US.